Our collaboration with the Children’s Hospital of Philadelphia is featured in today’s Philadelphia Inquirer!
The article highlights how our teams worked together to study complement factor I deficiency—an ultra-rare genetic disorder found at much higher rates in the Amish community—and its connection to life-threatening conditions such as brain swelling.
Read the published research paper
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Researchers from Children’s Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population. These findings could help clinicians better recognize the disease and develop a standard-of-care, particularly for Amish patients affected by this disease. The findings were recently published by the Journal of Allergy and Clinical Immunology.
To read the full press release, please visit HERE.